About Emphron Informatics
Emphron Informatics is a boutique bioinformatics consultancy, operating worldwide though based in the Asia Pacific region. We were founded in 2003 by Dr Mervyn Thomas, who has over 25 years experience in bioinformatics -- in both the private sector and public sector research agencies.
Our services include strategic consultancy in informatics, service data mining for large and complex biological and biotechnology data sets, training, staff development and capability building, and technology evaluation and skills audits.
Clinical Trial Statistics
We provide high level statistical consultancy to ensure that trial protocols satisfy the complex set of clinical, regulatory and commercial objectives which you face. We understand your business problems, and we deliver effective solutions.
We have experience across the spectrum of clinical research, from investigator-led clinical studies through to phase III trials, and across many therapeutic areas.
We have solid experience in the discovery and development of diagnostics. We operate across the spectrum from discovery using modern genomic and proteomic platforms, through assay optimisation to the design and analysis of diagnostic clinical trials. We have experience negotiating the design of diagnostic trials with the FDA.
Genomics and Proteomics
We have substantial experience across the range of genomic platforms including: Affymetrix, Combimatrix, Illumina and RTPCR based platforms. We cover the spectrum of activities through study design, data management, quality assurance, differential expression, ontology analysis and study reporting. We use state-of-the-art tools and techniques.
We also have experience in a range of proteomic technologies including mass spectroscopy, 2D electrophoresis gels, FACS and antibody arrays.
Dr. Mervyn Thomas
Founder and partner - Biostatistics
Prior to founding Emphron Informatics, Mervyn was the founding manager of the Bioinformatics Research Programme of CSIRO Mathematical and Information Sciences. He had, in fact, established the research programme. As programme manager, Mervyn was responsible for developing and integrating research and commercialisation strategies. The programme remains a viable and successful research activity within CSIRO. Its main focus is on developing and commercialising new techniques for massively multivariate data mining.
Before joining CSIRO in 1991, Mervyn managed the Mathematics and Statistics group of Shell's Sittingbourne Research Centre. He was Shell's most senior Biostatistician. Under his direction, the statistics research group targeted advanced chemometric methods for molecular design and he focused on in-silico discovery and evaluation.
Before joining Shell, Mervyn was a senior statistician working in pre-clinical pharmaceutical development and agrochemical development for ICI (now Zeneca).
Dr. Allan Rae
Partner - Information Systems
Allan has been leading Emphron's software development and clinical data management services since joining the company in 2007. Prior to this, Allan completed a PhD in Electrical Engineering (Computer Systems) at The University of Queensland. While there Allan worked within the School of Information Technology and Electrical Engineering technical support group. In that group he built and maintained an application to allow laboratory managers to build custom system software images for their computer laboratories. These system images could then be deployed en mass by staff or as needed by students.
Allan's many years of SunOS, Linux and FreeBSD system administration and software development experience ensure stable server and development environments and quality coding practices are maintained throughout Emphron. Allan has made significant contributions to the LyX open source project (core member 1997 to 2003) and to various niche projects including libsigc++ (up to version 1.2) and xtl. These experiences in working in globally distributed development teams have reinforced the need for good source code management practices, product testing and, of course, communication.
Allan started his working career in industrial process control and automation at Mount Isa Mines as an apprentice Instrument Fitter. He later worked for a subsidiary as an Instrumentation Engineer. Maintaining the process control systems of power stations, smelters and mineral processing plant for which downtime could easily cost in excess of $100,000/minute and risk lives reinforced Allan's drive for efficiency, optimisation and automation.
Emphron has a solid reputation for statistical analysis and interpretation you can trust.